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On behalf of the Organizing Committee it is our pleasure to welcome you to the 13th International Conference on Calixarenes “Calix 2015” taking place in Giardini Naxos (Italy) from Sunday 5 to Thursday 9 July 2015. The conference aims to provide a comprehensive survey of both fundamental and applied research in the field of calixarenes and related macrocyclic compounds. In keeping with its 22-year-long history and its own friendly and casual tradition, this five-day event brings together scientists, academics and students from around the globe to present their current research and discuss and shape the future challenges of the field. The conference features the first C. David Gutsche Award lecture, three plenary lectures, as well as invited and short lectures delivered by top-tier international scientists. The program will also include a number of flash presentations that have been selected from among the contributions submitted for the poster session.