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The symposium is intended to bring together researchers in the areas of the mechanics of defects (cracks, dislocations, inclusions, precipitates, phase boundaries, shape optimization etc.) and the material (configurational) mechanics in the sense of Eshelby, as a rational framework for the description of driving forces on evolving inhomogeneity and structural changes in continua. Important developments in Configurational Mechanics have been performed in the last years and the symposium aims both at exchanging scientific knowledge and experience as well as to initiate and continue new and existing friendships between leading researchers in the field of Applied Mechanics. The contributions are expected to be on the highest scientific level as in the previous meetings.