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Sections: I. Structural basis of muscle contraction. Mechanism of actin-myosin interaction. II. Sarcomeric proteins: structure and function. III. Muscle plasticity and signaling pathways. Exercise, disuse and pathology. IV. Synaptic plasticity. Membranes, pumps and ion channels. V. Integrative Motility. Motor control and motor behavior. VI. Non-muscle motility. Cytoskeleton and control of cellular functions. VII. Cardiac and smooth muscle in health and disease.