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AFMC-AIMECS meetings are the most important international event organized by the Asian Federation for Medicinal Chemistry (AFMC) on the biennial years since its first meeting held in Japan in 1997. AFMC-AIMECS meetings provide a very important and beneficial opportunity for the medicinal chemists to stimulate the exchange of ideas, and to evaluate new methods and new lines of investigation for the contribution to the global progress of drug design and development. Following the traditions of AFMC-AIMECS meetings, the 12th AIMECS 2019 will also provide an international forum for presentation and discussion, by both highly skilled professionals and young scientists from academia and/or industry by featuring invited lectures, oral talks and poster presentations of recent progress and future trends in all aspects of Medicinal Chemistry.