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The conference dates back to 1999 when its inaugural session “Structure and stability of proteins” was held as a small local meeting. As participation grew over two decades, the event has evolved into an international multidisciplinary platform that brings together scientists from different areas. The programme of the meeting is intended to provide an opportunity for both junior and senior scientists to stimulate discussions in a broad spectrum of topics including molecular biophysics, biochemistry, biology and protein chemistry. Attention will be also paid to the recent status, development, and future research trends in bio- and nanotechnologies.