ИСТИНА

• Охват: Международная
• Даты проведения: 11-14 сентября 2011
• Место проведения: Safed, Israel
• Организатор:
  Weizmann Institute
• Число участников: 100
• Число докладчиков: 26
• Веб-сайт: http://www.weizmann.ac.il/conferences/dnasearch/general.html
• Описание конференции:

  The recent advances in biochemical, biophysical as well as computational and theoretical studies of the mechanism of DNA search and its implications on cellular functions make it a very timely event. Following the seminal paper by Peter von Hippel in 1981, numerous studies have addressed the question of the unexpected fast recognition between protein and DNA that is faster than the rate predicted for a reaction controlled by 3D diffusion. The developments of single-molecule techniques, cell biology, and theoretical formalisms enormously contributed to better understanding of the driving forces and basic principles of protein-DNA interactions which govern many regulatory cellular functions. The workshop will provide an exciting forum to discuss new developments, both experimental and theoretical, as well as open questions in the fields of protein-DNA recognition and in particular the mechanisms of facilitated diffusion, both in vitro and in vivo. In addition to the invited presentations from leaders in the field, the workshop will provide opportunities for junior scientists and graduate students to present their work via abstract-selected presentations and poster. Topics to be discussed in the workshops: Kinetics and mechanisms of DNA search by proteins and their implications on cellular processes Molecular and biochemical details of DNA search: the effects of the geometry and flexibility of the proteins and DNA Theoretical and computational studies of DNA search Single-molecule studies of protein-DNA interactions and of the facilitated diffusion DNA search in vivo: the effects of cellular crowding, DNA packing, roadblocks on the DNA, etc.

• Добавил в систему: Sheinman Michael

Доклады:

• 2011 Efficient DNA search (Пленарный)
• Автор: Sheinman M.