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The IMMC12 is organized by the University of Bari “Aldo Moro” and by the Italian Society for Medicinal Mushrooms (SIFM). The title of the Conference is “Medicinal mushrooms: the bet for the future of humanity” in order to create focus, in addition to the topics already covered in previous editions, especially on clinical studies to legitimize the use of medicinal mushrooms not only in integrated medicine but also among Medical Scientific Societies. The aim is also to engage, empower, evolve and explore knowledge among both academics and industry personnel. Another goal of IMMC12 is to engage young people, facilitate face-to-face meetings and increase their interest in medicinal mushrooms and their different applications.