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Notes on the organization of the Workshop: The members of the International Organizing Committee are: S. Varfolomeyev (Russia) Co-Chairman F. T. Robb (USA) Co-Chairman E. Bonch-Osmolovskaya (Russia). M. J. Danson (UK) D. Grogan (USA) G. Karpov (Russia) K-O. Stetter (Germany) E. Mather (USA) P. Mattila (Finland) E. Rainina (USA) E. Sverdlov, (Russia) J. Wiegel (USA) I. Gachok, (Scientific Secretary of the Organizing Committee), Program August 7, Monday 9.00: Opening Cochairs F. T. Robb, S.D. Varfolomeyev Phylogeny and Biodiversity 9.10-10.00 K-O. Stetter Metabolism and phylogeny in hyperthermophiles 10.00-10.45 E. A. Bonch-Osmolovskaya Microbial processes in thermal environments studied with radioisotopic methods 10.45-11.15 Coffee-break Co-chairs K-O. Stetter, E. A. Bonch Osmolovskaya, Genetics and Genomics 11.15 D. Grogan Archaeal genetics at high temperature and low pH 11.45 F. T. Robb Genomic survey of the CO-utilizing bacterium, Carboxydothermus hydrogenoformans 12.15 C. Schleper Environmental genomics: investigating the properties of uncultivated microorganisms at the genotypic level. 12.45 Lunch Cochairs: J. Wiegel, R. Ronimus Ecology and Physiology 14.00 D. L. Maeder Inverse ecology in Pyrococcus spp 14.30 M. L. Miroshnichenko Isolation of novel anaerobic, thermophilic bacteria from the deep-sea hydrothermal areas 14.50 T. Torok Preliminary characterization of the microbial diversity in water, sub-bottom sediment, and hot spring samples at Lake Baikal in Russia 15.10 Coffee-break 15.40 T. Sokolova Diversity of thermophilic carboxydotrophic anaerobic H2 producing bacteria. 16.20 J. Wiegel Chemolithotrophic Fe (III) reducing isolates from Yellowstone National Park. 16.50 R. Ronimus Aerobic bacilli isolated from Antarctic and New Zealand thermal environments 17.20 G. A. Karpov Geo-physical features of the Uzon - What to expect on the field trip. 17.40 Dinner 18.40 Round Table: Co chairs J. Varley and E. Mathur "Bioprospecting, Benefit Sharing and the Convention of Biological Diversity" August 8, Tuesday Field excursion After Dinner Presentation G. Karpov, (30 min) “Physical-chemical parameters and biocenoses of thermal systems” August 9, Wednesday Chair: J. R. Wild High-Temperature Biocatalysis 9.00 S. D. Varfolomeyev Protein biodiversity: paradoxes of enzyme active site structures 10.00 T. Haertle Influence of amphiphiles on molecular forms and on activity of proteinase from Pyrococcus abyssi. 10.20 R. Ronimus Phosphofructokinase Evolutionary Studies 10.50 Coffee-break Chair F. T. Robb Applications in enzymology and bioremediation 11.20 J. R. Wild Ancillary functions for prime-time enzymes 11.50 J. H. Wolfram Culturing, physiology and bio-process development for a unique microorganism isolated from a contaminated soil sample 12.10 J. M. Blamey Pyruvate ferredoxin oxidoreductase from the hyperthermophile Pyrococcus woesei 12.40 Lunch Cochairs: C. Schleper, K. Stedman Genetic transformations 15.00 K. Stedman. Transformation of Sulfolobus solfataricus with viral vectors 15.30 N. G. Belogurova Cryptic plasmid pNB2 from Clostridium thermosaccharolyticum Co-chairs S. D. Varfolomeyev, E. Rainina Improving and Monitoring 16.00 A. Lebedinskii Nested PCR as a method for monitoring creanarcheota in mixed culture 16.20 E. Rainina Simple and reliable method to increase thermophiles operational stability. 17.10 A. Eremenko Electrochemical flow injection biosensor-based analyzer 17.40 I. Kurochkin Fiber-Optic Luminiscent Oxygen Sensor 18.10 Dinner August 10, Thursday Field excursion After Dinner Presentation R. Hoffman (30 min) “Chemistry’s essential tension: The same and not the same” August 11, Friday Cochairs: P. Mattila, D. Grogan DNA Polymerases 9.00 A. Wang Sampling Nature's Diversity: Identification of Naturally Occurring Thermophilic DNA Polymerases with Altered Nucleotide Discrimination Properties 9.30 W. Ankenbauer DNA polymerase from Thermococcus gorgonarius 10.00 N. Kurosawa Cloning and expression of family B DNA polymerases of thermoacidophilic crenarchaeon Sulfurisphaera ohwakuensis 10.20 Coffee-break 10.50 A. Gardner Determinants of modified nucleotide base recognition in archaeal DNA polymerases 11.20 M. Eldarov Chimeric gene containing domains from Thermotoga neapolitana and “Anaerocellum thermophillum" pol genes: construction and properties 11.40 F. Perler Protein splicing: evolution, distribution and new insights into the mechanism 12.10 Lunch 13.30 Field Excursion and Farewell Party August 12, Subboty