ИСТИНА

The formation of hydroxyapatite nanocrystals occurs at the place of mixing of calcium hydroxide and phosphoric acid. The interaction between sound waves in the reactor, containing solution of calcium hydroxide, and the jet of phosphoric acid pumped into the reaction mixture, creates vortices at the interface between reagents. Low intensity, high frequency ultrasound in the absence of cavitation, creates smaller vortices compared to the process without ultrasound. As a consequence, the smaller size of nanoparticles formed at the interface of the reagents in the presence of acoustic waves. The discovered method of synthesis has a potential to control nanoparticles size by acoustic or hydrodynamic means.