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This work presents the technique and results of computer simulation of the interaction of cosmic radiation with telescopic detectors. The program code based on Geant4 libraries is designed, to simulate the operation of the detector of ionizing radiation, consisting of several sequentially located semiconductor and scintillation detectors. Using the Geant4 toolkit, we simulate signals from electrons and protons of various energies in the detecting regions of the device, taking into account the generation of secondary particles. Separation of signals from primary particles passing through the entrance window of the telescope and through the walls of the housing is carried out. The obtained data are used to simulate the necessary throughput of the device electronics. The characteristics of the sensitivity and accuracy of the spectrum determination are performed using an original algorithm. This algorithm realizes quantile regression to obtain information on the spectra of cosmic radiation, based on the energy losses of particles in the detectors of the instrument. We can definitely separate signals from electrons and protons but there are some problems with determination of electron energy when using such detectors. The combination of discussed software packages allows optimizing the parameters of the geometry and logic circuits of the device. Application of the results obtained using the presented software codes at the design and production stages of detectors will significantly increase the reliability of received data. The source files of the program codes are available in the public domain.