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Genetic variations of serotonin transporter gene (5HTT) are closely related with human adaptive ability to control emotion and very attractive in investigation of athletes whose life is accompanied by high emotional pressure. Present study investigated the effect of genetic polymorphism of 5HTT on aggression of athletes, 86 synchronized swimmers and 83 non-trained female controls were genotyped. 73 (age 8-18) of synchronized swimmers are actively engaged in competition, 64 of them participated in psychological testing of aggression (Buss-Durkee Hostility Inventory). Analysis of primary of this test reveals, that Indirect Hostility is increased with both short alleles SS compared with other groups (SL and LL). Furthermore, it was shown that the frequency of 5HTT alleles in groups of elite athletes of different kind of specialization are differ between kind of sport and between athletes and control group. Interrelation of 5HTT genotype, aggressiveness and athletic successfulness are vigorously discussed.