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Palladium-catalyzed amination of aryl and heteroaryl halides is a powerful tool for creating C(sp2)-N bonds. As adamantane-containing amines and their heterocyclic derivatives are of great interest as physiologically active compounds, we investigated the catalytic N-heteroarylation of some amines with adamantane fragment using dihalopyridines. Previously obtained data with 2-bromopyridine demonstrated a pronounced dependence of the reaction result on the nature of the adamantine-containing amine [1]. Here we have found out that symmetrical 2,6- and 3,5-dihalopyridines successfully produce mono- and diamino derivatives depending on the stoichiometry of starting compounds. Generally, better results were obtained with 2,6-dichloropyridines in comparison with 2,6-dibromopyridines.