ИСТИНА

Chemical, physical and mechanical compatibility of osteoconductive biomaterials for orthopaedics is a primary goal for one of the important areas of modern materials science. A bone graft material should be used as a porous active medium (scaffold), necessary for the construction of newly-formed tissue. An ideal implant should gradually dissolve and be replaced by the new bone tissue and supply inherent events for nerve and vessels regeneration during rehabilitation. The production of an implant for tissue regeneration with complex matrix framework and optimal architecture is unavoidably linked with additive manufacturing techniques. This talk tackles interdisciplinary character of the issue, being at the intersection of materials science, medicine and engineering. Touching different additive manufacturing approaches for fabrication of personalised implants for bone tissue reconstruction and the significance of interconnected pore architectonics for the guiding and the supporting function at the initial stages of osseointegration of the implant. RFBR partially supported this study under Grant No. 16-38-60203, 18-53-00034, 18-29-11079, 18-29-11070, 18-33-00789, 18-08-01473, 19-03-00940. Russian Science Foundation partially supported this study under Grant No. 17-79-20427, 18-79-00256. The authors acknowledge partial support from MSU Program of Development