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The efficient integration of target bioanalyte with a nanostructured electrode surface within man-made electrochemical devices is a crucial aspect when engineering (bio)analytical devices. Generally, integration efficiency determines the quality of an analytical electrochemical device, its sensitivity, and eventially its market competitiveness. Carbon nanomaterials have been widely incorporated to improve layer conductivity and increase the efficiency of electron exchange on the surface of carbon-based electrodes, Both electrodes and carbon nanomaterials are highly hydrophobic, rendering an easy and reproducible modification of electrode surfaces rather challenging. This challenge can be solved using amphiphilic polymers like poly(ionic liquid)s or diblock copolymers, the latter featuring one hydrophobic and one hydrophilic (often ionic) block. The hydrophobic segment(s) of such polymers can adhere to the surface of the electrode or carbon nanomaterials, while the hydrophilic moieties ensure dispersability of carbon nanomaterials in aqueous media and/or can serve as a non-destructive matrix for the subsequent embedment of (bio)molecules. Nanosized thin polymer films can be constructed directly on the electrode surfaces via adsorption, which is to a great extent determined by the state and structure of the initial surface and/or the pre-adsorbed layers and ruled by different conditions (pH, salt composition, etc.). To demonstrate this, different fabrication regimes and properties of thin polymer/enzyme films deposited onto conductive substrates were examined. This work also reports successful solubilization of carbon nanomaterials in aqueous media, using poly(ionic liquid)s or ionic amphiphilic diblock copolymers. Benefecial surface modification of electrodes by fine aqueous dispersions of carbon nanomaterials provides a considerable improvement of (bio)sensor performance. Examples of advanced direct electrochemical analysis of low molecular weight substances (biochemical substrates, drugs, etc.) and biomolecules (nucleic acids and hemoproteins) are considered. (5.10, p. 81)
№ | Имя | Описание | Имя файла | Размер | Добавлен |
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1. | program | Extended_Programme_Polychar27.pdf | 3,3 МБ | 12 декабря 2019 [Sigolaeva_Larisa] |