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Introduction: The study of sociocultural mediation of the state of one's health involves the consideration of subjective assessment of physical health depending on gender differences. Objectives: Identification of features of the subjective assessment of physical health in men and women. Methods: The study involved 210 men and 403 women aged 14 to 76 years (m = 26.9; SD = 13.7) from 6 regions of the Russian Federation: Moscow, St. Petersburg, Udmurtia, Sakha, Sverdlovsk and Kemerovo regions. Respondents were asked to evaluate their physical health at the present time, choosing one of the following answers: "excellent", "good", "average", "poor", "very poor". Results: It was found that in men the most frequent answer was "good" (43%), followed by "average" (31%), "excellent" (18%), "poor" (8%), and "very poor" (1%). In women, themost common answer was "average "(41%), followed closely by "good" (39%), and then – "excellent" (13%), "poor" (7%), and "very poor" (0.5%). Statistical analysis on a rank scale using the t-test for independent samples showed that the differences in the assessment of their physical health in men and women are expressed at the level of tendency (t = 1.783; p = 0.075). Conclusions: Thus, men and women are similar in that they rarely choose the extreme answers for assessing physical health. In moderate assessments there are gender differences at the level of tendency: men often choose the answer "good", and women – "average". The study was supported by the Russian Foundation for Basic Research, Grant 17-29-02506. Conflict of interest: No Keywords: health; Gender; sociocultural determination; subjective assessment