ИСТИНА

The reason for the formation of a danger to the health of consumers of agricultural raw materials and products may be the presence of natural and synthetic toxic substances in them, which accumulate as a result of the treatment of plants with protective agents and as a result of damage by pathogenic microorganisms that carry out the biosynthesis of toxins. These compounds include various pesticides and mycotoxins, which are synthesized by various mycelial fungi that infect raw materials and products at various stages of their production and storage. As a modern and effective approach to ensuring the biosafety of such raw materials for humans, aimed at eliminating toxins through their degradation during enzymatic hydrolysis [1,2] attracts more and more attention. To select enzymes capable of catalyzing the decomposition of various toxins as efficiently as possible, molecular docking methods are actively used [3-6], allowing virtual screening among possible candidates and predicting the probability of effective catalysis. It has been established that poly(amino acids), antioxidants, peptides with antimicrobial activity can be used as stabilizers for such enzymes. The decomposition of toxins differing in chemical properties has been experimentally confirmed, and the additionally acquired functionality of the created enzyme preparations has been established depending on their stabilizers.