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We performed studies on the oxidation of NC with a nitrogen content of 10.7 and 13.38 wt% using Desulfovibrio desulfuricans. Incubation of NC on bacteria was carried out for up to 65 days. The oxidation of NC was carried out using a mycelial fungus of the genus Fusarium solani IFO 31093. It was shown that in the presence of F. solani, the N content was 10.61% (16 days) and 10.51% (38 days). The decomposition of NC was indicated by the appearance of nitrate and nitrite groups in the culture medium - 11.4 mcg/ml and 3.38 mcg/ml. After 5 days of F. solani incubation, the proportion of low molecular weight products was 15%, by 65 days the molecular weights of these fragments had significantly decreased, which is promising from the point of view of practical application.