ИСТИНА

In presented study a series of new branched block copollactides and their amphiphilic derivatives were synthesized and studied in respect to their physical-chemical and surface properties. It was established that all synthesized amphiphilic block copolymers possess pronounced surface properties depending on the ratio of the hydrophilic and lipophilic moieties in the macromolecule, as well as on the architecture of the copolymer. We present the successful use of biodegradable aliphatic copolyesters as surfactants for the preparation of microemulsions, and microparticles. It has been found that the size of emulsion droplets, stabilized by the branched copolymers, grew more slowly than emulsions stabilized linear copolymers. Microcapsules obtained using the branched copolymers as surfactants show a higher encapsulation efficiency as compared to those generated using linear copolymers.