ИСТИНА

At the present stage of scientific and technological development, the application of complex molecular and supramolecular systems plays a decisive role. Tricarbocyanines are supposed to be used for the detection of aldehydes by the mean of fluorimetric determination. The meso-modified dye must contain a free amino group in the structural fragment associated with the conjugated fluorophore system. Thus, the fluorescence build-up is provided as a result of the binding of the amino group to the carbonyl group. In this work, we propose an approach to the synthesis of conformationally fixed tricarbocyanine dyes modified at the meso-position both with a free amino group and included in the aromatic system (para- and meta-aminophenols). An analysis of their physicochemical properties showed that new fluorophores having a free amino group in direct conjugation with the polymethine system are promising analytes for the determination of aldehydes due to efficient binding to the carbonyl group, accompanied by fluorescence enhancement.