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An approach that combines numerical modeling with measurements is gaining acceptance for field characterization in medical ultrasound. The general method is suitable for accurate simulation of the fields radiated by therapeutic transducers in both water and tissue. Here, three characterization methods are compared. Simulations based on the 3D Westervelt equation with a boundary condition determined from acoustic holography measurements are used as the most accurate benchmark method. Two simplified methods are based on an axially symmetric nonlinear parabolic formulation, either the KZK equation or its wide-angle extension. Various approaches for setting a boundary condition to the parabolic models are presented and discussed. Simulation results obtained with the proposed methods are compared for a typical therapeutic array and a strongly focused single-element transducer, with validation measurements recorded by a fiber optic hydrophone at the focus at increasing acoustic outputs. It is shown that the wide-angle parabolic model is more accurate than the KZK model in governing diffraction effects in the nearfields of the focused beams. However, both methods give accurate results in the focal zone, even at very high outputs when shocks are present. [Work supported by and RSF 14-12-00974, P01 DK043881, NIH EB7643, and NSBRI through NASA 9-58.]