ИСТИНА

The production of the carbon-13 isotope by the laser method, implemented in Russia, demonstrated the efficiency of such a process with the production of a heavier carbon isotope with a concentration of 35 - 55% at. Further enrichment up to 99% at. of 13C, which is necessary for the application 13C in the clinical medicine noninvasive breath tests for metabolic research and diagnosis) and in fundamental science metabolic pathway research, including inborn errors of metabolism; a fundamental reaction in organic chemistry), was performed by a gas centrifugal method. Unfortunately, the use of two physical methods for separating the isotopes of a light chemical element in one technological chain could not lead to competitive production in comparison with physicochemical separation methods, in particular, with the carbon monoxide distillation /3/. The report is devoted to the analysis of the application of the chemical isotope exchange method in a system the gaseous CO2  solution of aminocarbamate in an anhydrous organic solvent for the final enrichment of 13C together with laser separation of carbon isotopes, as well as using of chemical exchange to enrich 13C from the natural level. At the same time, options for technological solutions aimed at intensifying the chemical-exchange for 13C enrichment process, including the construction of separation cascades, are considered. For several variants of the organization of 13C enrichment process, the results of an economic estimate of the costs of obtaining this isotope are given