|
ИСТИНА |
Войти в систему Регистрация |
ИПМех РАН |
||
Generation of α-haloalkyl radicals from B-(α-haloalkyl)pinacolboranesдипломная работа (Бакалавр)
- Научные руководители: Andrey Kuzovlev, Philippe Renaud
- Автор: Matthias Pfaeffli
- Тип: Бакалавр
- Организация, в которой проходила защита: Universität Bern, Philosophisch-naturwissenschaftlichen Fakultät, Departement für Chemie und Biochemie
- Год защиты: 2017
- Аннотация: The generation of α-haloalkyl radicals from B-(α-haloalkyl)pinacolboranes has been investigated. To form the initial substrates, appropriate methods like the iridium hydroboration, “on water” borylation and the synthesis catalyzed by Schwartz's reagent were used. Then Matteson homologation leads to the formation of radical sourсe - B-(α-haloalkyl)pinacolborane. Following radical halogenation with PhSO2X provided the desired gem-dihalides. This method demonstrated moderate to high yields when primary, secondary, non-activated and activated alkenes containing electron donating or withdrawing groups were used as starting compounds.
- Добавил в систему: Кузовлев Андрей Сергеевич