Antibody Developments and Immunoassays for Organophosphorus Chemicals: A Reviewстатья
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Дата последнего поиска статьи во внешних источниках: 20 марта 2018 г.
Аннотация:Immunoassays for organophosphorus (OP) chemicals are now well-established techniques, and they meet the demand for rapid, simple, cost-effective on-site analysis. Haptens, antibodies, and labels are the key components of immunoassays for OP chemicals. This review gives an overview of the design and synthesis of immunizing and coating haptens, coupling of haptens to a carrier, reported antibodies against OP chemicals (e.g., polyclonal, monoclonal and recombinant antibody), and traditional and novel labeling materials for immunoassay signal detection (e.g., radioactive isotope, enzyme, fluorescent compound, and colloidal gold). In addition, we discussed future considerations and opportunities for advancing the development of immunoassays for OP chemicals