|
ИСТИНА |
Войти в систему Регистрация |
ИПМех РАН |
||
A Relaxation Model of Ideal Folding in a Homogenous Viscous Mediumстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 марта 2016 г.
- Автор: Shaitan K.V.
- Журнал: Biophysics
- Том: 60
- Номер: 5
- Год издания: 2015
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 692
- Последняя страница: 700
- DOI: 10.1134/S0006350915050206
- Аннотация: The problem of the 3D structure of the interacting nodes in a model polymer chain has been studied in terms of the theory of stochastic dynamics. A variational principle is formulated for elementary displacements and the velocities of conformational movements as well as its implications for the folding of a polymer chain in a viscous medium. The result is a maximally smooth decrease in the potential energy of the system during its conformational relaxation (the timid mountain skier principle), which is consistent with the Onsager principle of the least dissipation of energy for the kinetics in weakly nonequilibrium systems. The model predictions agree with the molecular simulations for similar systems. The relationships between the structure of multidimensional potential energy surface and folding kinetics are discussed. The model of a parabolic energy funnel that is formed by nonbonded interactions between chain nodes is developed. The relaxation folding kinetics in a parabolic model of the energy funnel is close to the exponential law.
- Добавил в систему: Шайтан Константин Вольдемарович
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | перевод | 5_2015_shaitan_eng.pdf | 255,9 КБ | 14 декабря 2015 [ShaitanKV] |