|
ИСТИНА |
Войти в систему Регистрация |
ИПМех РАН |
||
Hybridization of COBAC, QSPR / QSAR and SBGN Technologies: The Unity of Theory and Practice for Biomedical Technique Design and Biochemical Diagnostic Information Analysisстатья
- Авторы: Orehov T.C., Gradov O.V.
- Журнал: Journ. Med. Bioeng
- Том: 5
- Номер: 2
- Год издания: 2016
- Первая страница: 128
- Последняя страница: 132
- DOI: 10.18178/jomb.5.2.128-132
- Аннотация: A current global trend in the development of biomedical and pharmaceutical chemistry is the use of computerized analytical technologies like COBAC, typically followed by the comparison with the action of the known alalytes using QSAR / QSPR methods. The clinicians are interested not in the results of the primary measurements, but in representative results of the physiological and biochemical tests compared with the preceding drugs and their analogs. In this case a direct conversion of numerical data into the QSAR / QSPR descriptor values with their subsequent transformation to the qualimetric results is necessary, which is described in this paper. We would also like to underlie that the innovation of our work is in the concept proposed which for the first time combines the principles of COBAC, QSPR / QSAR and SBGN, but not in the technical realization or program code itself.
- Добавил в систему: Gradov Oleg V.