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LOCALIZATION OF SITES OF DNA ATTACHMENT TO THE NUCLEAR MATRIX IN THE DOMAIN OF THE CHICKEN ALPHA-GLOBIN GENES IN FUNCTIONALLY ACTIVE AND FUNCTIONALLY INACTIVE NUCLEIстатья
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 мая 2015 г.
- Авторы: Razin S.V., Rzeszowska-Wolny J., Moreau J., Scherrer K.
- Журнал: Molecular Biology
- Том: 19
- Номер: 2
- Год издания: 1985
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 376
- Последняя страница: 384
- Аннотация: Short DNA fragments remaining associated with the nuclear skeleton after nuclease treatment and high salt extraction of chicken erythroblasts and erythrocytes nuclei were used as hybridization probes in order to find the positions of DNA attachments to a nuclear skeleton inside the domain of alpha-globin genes. It is found that in erythroblasts nuclei a rather long region including coding sequences is associated with the nuclear skeleton. This region coincides with the region preferentially digested by DNAase I in chromatin. In erythrocytes nuclei, a specific attachment point is found in the region between 4500 and 300 bp upstream to pi-gene. Several attachments in this region are detected also in erythroblast nuclei, but they are not prominent in this case. The results are discussed in terms of the existence of stable (structural) and temporal (functional) attachments of DNA to the nuclear skeleton.
- Добавил в систему: Разин Сергей Владимирович