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Magnesium Deficiency Effect on the Severity of Autonomic Dysfunction in Mitral Valve Prolapse Patients with Emotional Tensionстатья Тезисы
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или ScopusДата последнего поиска статьи во внешних источниках: 22 февраля 2019 г.
- Авторы: Pervichko E., Martynov A., Pak L., Akatova E.
- Журнал: International Journal of Psychophysiology
- Том: 131
- Номер: 10
- Год издания: 2018
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 140
- Последняя страница: 141
- DOI: 10.1016/j.ijpsycho.2018.07.377
- Аннотация: Background.Urgency of this research is due to the hypothesis of a relationship between the clinical manifestations of mitral valve prolapse (MVP) and magnesium (Mg) deficiency [Durlach, 1998]. The purpose of this study was to test a severity of autonomic dysfunction (AD) and emotional tension (ET) in MVP patients before and after the treatment with magnesium orotate.Methods.The study involved 43 MVP patients with AD (the average age was 26.7±2.6) and 73 healthy subjects (the average age was 27.5±1.3). All of MVP patients receive treatment with magnesium orotate at a dose of 3000 mg per day (a 6-months course). Psychological testing was carried out using the MMPI, the Cattell's 16 PF Questionnaire, and the Spielberger State-Trait Anxiety Inventory. The AD severity was detected with ‘Questionnaire for AD signs diagnostics’ (Vein, 2003). Quantification of Mg in hair was carried out on Laser-Induced Br eakdown Spectrometer «LIBS-ELITE» (GMB, Australia). Results.The MMPI midrange profile for MVP patients is characterized by significant (p<0.01) differences with healthy participants for the 1, 2, 3, 6, 7, 8, and 0 scales. We obtained lower (p<0.05) values for the A, C, E, F, and H factors and higher (p<0.05) values for the O, Q2, and Q4 scales for MVP patients in 16 PF. These data demonstrated that most MVP patients are distinguish from healthy participants by anxiety level, emotional lability, self-distrust, increased sensitivity to one’s failures, and a tendency to lose control over emotions. This set of features testify to an enduring state of ET.Before the treatment, mild D - in 51.9% of patients. A significant correlation (p <0.01) was found between the height of trait anxiety and AD severity. After the treatment, a significant decrease in AD severity was noted. Severe AD was not detected in any patient. Mild AD was diagnosed in 59.3% of cases. Mg concentration was decreased in 72.7% of patients before the treatment. Mg concentration averaged for the MVP group was 59.4+9.25 μg/g. After a 6-month course of therapy Mg level compared to the baseline increased and reached the lower limit of normal in 62.5% of patients. These patients had clinically significant reducing the severity of AD and ET reducing.Conclusion.The results confirmed the hypothesis of a relationship between the severity of AD and anxiety disorders with Mg deficiency in patients with MVP.
- Добавил в систему: Первичко Елена Ивановна