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INVOLVEMENT OF PROTEIN SYNTHESIS IN THE RECONSOLIDATION OF MEMORY AT DIFFERENT TIME POINTS AFTER FORMATION OF CONDITIONED REFLEX FREEZING IN MICEстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 10 апреля 2019 г.
- Авторы: Muraveva E.V., Anokhin K.V.
- Журнал: Neuroscience and Behavioral Physiology
- Том: 37
- Номер: 4
- Год издания: 2007
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 411
- Последняя страница: 417
- DOI: 10.1007/s11055-007-0028-1
- Аннотация: The aim of the present work was to study the involvement of protein synthesis in the reconsolidation of memory at different periods of time after training. In mice trained in a conditioned reflex freezing model, memory was reactivated by a reminder combined with administration of the protein synthesis inhibitor cycloheximide. The results showed that suppression of protein synthesis on reactivation of memory 3, 6, and 24 h and 14 and 30 days after training impaired acquired conditioned reflex freezing. These data provide evidence that memories retrieved by a reminder require protein-dependent reorganization at both short (3-6 h) and long (14-30 days) periods after training.
- Добавил в систему: Анохин Константин Владимирович