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Population Genomics Reveals Low Genetic Diversity and Adaptation to Hypoxia in Snub-Nosed Monkeysстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 декабря 2018 г.
- Авторы: Zhou Xuming, Meng Xuehong, Liu Zhijin, Chang Jiang, Wang Boshi, Mingzhou Li, Wengel Pablo Orozco-ter, Tian Shilin, Wen Changlong, Wang Ziming, Garber Paul A., Pan Huijuan, Xinping Ye, Xiang Zuofu, Bruford Michael W., Edwards Scott V., Cao Yinchuan, Shuancang Yu, Gao Lianju, Cao Zhisheng, Liu Guangjian, Ren Baoping, Shi Fanglei, Peterfi Zalan, Dayong Li, Baoguo Li, Jiang Zhi, Junsheng Li, Gladyshev Vadim N., Ruiqiang Li, Ming Li
- Журнал: Molecular Biology and Evolution
- Том: 33
- Номер: 10
- Год издания: 2016
- Издательство: Oxford University Press
- Местоположение издательства: United Kingdom
- Первая страница: 2670
- Последняя страница: 2681
- DOI: 10.1093/molbev/msw150
- Аннотация: Snub-nosed monkeys (genus Rhinopithecus) are a group of endangered colobines endemic to South Asia. Here, we re-sequenced the whole genomes of 38 snub-nosed monkeys representing four species within this genus. By conducting population genomic analyses, we observed a similar load of deleterious variation in snub-nosed monkeys living in both smaller and larger populations and found that genomic diversity was lower than that reported in other primates. Reconstruction of Rhinopithecus evolutionary history suggested that episodes of climatic variation over the past 2 million years, associated with glacial advances and retreats and population isolation, have shaped snub-nosed monkey demography and evolution. We further identified several hypoxia-related genes under selection in R. bieti (black snub-nosed monkey), a species that exploits habitats higher than any other nonhuman primate. These results provide the first detailed and comprehensive genomic insights into genetic diversity, demography, genetic burden, and adaptation in this radiation of endangered primates.
- Добавил в систему: Гладышев Вадим Николаевич