Аннотация:Using method developed by us early for transformation of so called generalized Schrodinger equation with temporal derivation from nonlinear response, we consider self-action of femtosecond laser pulse in optical fiber with the help of computer simulation. For this problem, conservative difference scheme is proposed. An influence of time dispersion of nonlinear response on self-focusing of Gaussian pulse is investigated. A restriction of light intensity in focus due to influence of time dispersion of nonlinear response is shown.