Recent advances in the preparation of adsorbent layers for thin-layer chromatography combined with matrix-assisted laser desorption/ionization mass-spectrometric detectionстатьяИсследовательская статья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 14 февраля 2019 г.
Аннотация:This review is focused on planar chromatography hyphenated with mass-
spectrometric detection for analysis of low-molecular-mass solutes. Various kinds
of hyphenations are discussed with attention paid to the preparation of thin layer
plates suited both for the mass-spectrometric detection of the resolved solutes direct
from thin-layer plates and for indirect mass-spectrometric detection of the resolved
solutes, performed by scraping, extracting, purifying, and concentrating the analyte
from the thin-layer chromatography plate. Plates with monolithic layers are relatively
new for thin-layer chromatography but they can successfully be combined with mass-
spectrometric technique in a pursuit of comprehensive local sample composition infor-
mation. Preparation of monolithic layers of different porosity and structure based
on organic, inorganic, and composite materials is illustrated together with examples
of successful separation and detection of low-molecular-mass solutes by means of
matrix-assisted and surface-assisted laser desorption mass spectrometry.