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Manipulating selectivity of covalently-bonded hyperbranched anion exchangers toward organic acids. Part II: Effect of mono- and dicarboxylic amino acids in the internal part of the functional layerстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 мая 2019 г.
- Авторы: Anna Uzhel, Anastasia Gorbovskaya, Alexandra Zatirakha, Alexander Smolenkov, Oleg Shpigun
- Журнал: Journal of Chromatography A
- Том: 1596
- Год издания: 2019
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- Первая страница: 117
- Последняя страница: 123
- DOI: 10.1016/j.chroma.2019.03.006
- Аннотация: Four covalently-bonded hyperbranched anion exchangers based on poly(styrene-divinylbenzene) (PS-DVB) substrate with different structure of the functional layer were prepared using mono- and dianionic amino acids such as glycine, β-alanine, aspartic acid, and glutamic acid in the internal part of the functional layer. Selectivity of all anion exchangers toward weakly retained organic acids was investigated at different temperatures in order to evaluate the effect of the number of carboxylic groups in the functional layer and its hydrophilicity on the separation. It was found that dianionic amino acids used in the first modification cycle of hyperbranching provide the best resolution for mono- and divalent organic acids, which makes the number of carboxylic groups in the structure of amino acid a key factor in the separation of such analytes with covalently-bonded hyperbranched anion exchangers, while the role of amino acid hydrophilicity is not that significant. Stationary phases prepared using aspartic and glutamic acids provided baseline resolution for quinic, glycolic, acetic, lactic, formic, and galacturonic acids, which are not resolved to baseline with modern commercially available anion exchangers; the increase of temperature was found to be favorable for improving the resolution even further.
- Добавил в систему: Затираха Александра Валерьевна