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Biological Properties Of @ -3-Calcium Phosphate in The Aspect of Tissue Engineeringстатья
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 15 августа 2019 г.
- Авторы: Kharkova NV1*, Reshetov IV1, Zelianin AS1, Philippov VV, Sergeeva NS3, Sviridova IK4, Komlev VS
- Журнал: Research Journal of Pharmaceutical, Biological and Chemical Sciences
- Том: 3
- Номер: 9
- Год издания: 2018
- Первая страница: 218
- Последняя страница: 223
- Аннотация: 3- Calcium phosphate scaffold is a perfect structure for the bone tissue engineering as it has a chemical and crystal similarity to the bone mineral composition and it is a promising material for bone defects treatment. Some explorations in vitro with colonized cells and scaffold properties analysis for further experiment in vivo were performed during these studies. Experiments in vitro cytotoxicity acute assessment of given materials and dynamics of slew cells have been performed on cell line model of homologus pooled human antibody. The viability of HPHA in dynamic experiments was evaluated using the method To conduct the test in MTT-experiments in vitro at the end of cultivation HPHA on the conditioned plastic- HPHApolistirene (control) and on the samples of bioceramics (experiment). It was revealed that since 3 days monitoring the HHA pool on sample materials of that laboratory group exceeded advanced control units. When analyzing the process of change of the population in conditions of cultivation of HHA on samples of calcium phosphate bioceramics TCP until 4 weeks has shown to reach maximum growth of the pool of experiment both HPHA and control occurs, usually in the first week of the experiment, however, in the experimental group the process of cell expansion flows significantly harder than in the control. The results suggest that the samples of TCP have satisfactory adhesive abilities concerning cells and not toxic to these cells. Our scaffolds are a promising implant material to be used in bone tissue engineering
- Добавил в систему: Филиппов Владислав Владимирович