Circadian Changes in Cardiac Rhythm Structure in Decompensated Chronic Heart Failureстатья
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Дата последнего поиска статьи во внешних источниках: 12 января 2022 г.
Аннотация:Circadian changes in heart rhythm structure were studied in rats with decompensated heart failure (experimental group) using the telemetric system for ECG recording and analysis. Analysis of many-day ECG records showed the predominance of various mechanisms of heart rhythm regulation in experimental and control rats throughout 24 h. More severe dysfunction of neuroautonomic mechanisms of regulation in experimental rats was characterized by a circadian dynamics. Many-fold increase in the number of QT c intervals longer than 220 msec and the Tpeak-Tend, most pronounced in experimental animals at night and in the morning, indicated the maximally high risk of fatal ventricular arrhythmias, leading to sudden cardiac death.