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The effect of blood serum proteins from the seal on the analgetic action of narcotic analgesicsстатья
- Авторы: Aslaniants Z., Melik-Eganov G.R., Evstratov A.V., Ivanov M.P., Batrakov S.G., Korobov N.V., Iasnetsov V.V.
- Журнал: Biulleten' eksperimental'noi biologii i meditsiny
- Том: 112
- Номер: 11
- Год издания: 1991
- Первая страница: 503
- Последняя страница: 505
- Аннотация: The protein fraction isolated from blood of seal, Phoca groenlandica, has been found to produce hyperalgesic effect on rats exposed to thermic or electrocutaneous nociceptive stimulation, but fail to affect writhes provoked by intraperitoneal injection of acetic acid solution on mice. When combined with morphine, the fraction lowered completely its narcotic analgetic action in the above mentioned tests. On the contrary, these same proteins combined with promedol or fentanil enhanced and prolonged analgetic effect of the latter.
- Добавил в систему: Коробов Николай Васильевич