Combination of supercritical fluid extraction and gas chromatography-mass spectrometry: Determination of impurities extracted from tablet preparations of the benzodiazepine seriesстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:A method is proposed for the determination of moderately volatile organic impurities in pharmaceutical tablet preparations based on a combination of solvent-free supercritical fluid extraction (SFE) and gas chromatography-mass spectrometry. The composition of moderately volatile impurities is determined in pharmaceutical tablet preparations of the benzodiazepine series (diazepam, phenazepam, nitrazepam, and clonazepam).