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Relationship between Apoptosis and Expression of Heat Shock Proteins in Peripheral Blood Lymphocytes of Patients with Myocardial Infarctionстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 сентября 2016 г.
- Авторы: Konstantinova E.V., Khomyakova N.F., Konstantinova N.A., Podkolzina A.V., Sapozhnikov A.M.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 150
- Номер: 6
- Год издания: 2011
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 682
- Последняя страница: 684
- Аннотация: We studied activity and dynamics of apoptosis of peripheral blood lymphocytes in patients with myocardial infarction and analyzed the relationship of these processes with expression of heat shock proteins with a molecular weight of 70 kDa playing an essential role in preventing cell death. Thus, we fi rst demonstrated activation of apoptosis in peripheral blood cells of patients with myocardial infarction compared to the control (healthy individuals) and revealed the expected negative correlation between the expression of heat shock proteins with a molecular weight of 70 kDa by lymphocytes and intensity of their death. The observed dynamics of mononuclear cell apoptosis in the peripheral blood of patients with myocardial infarction can reflect activity of programmed cardiomyocyte death in the focus of ischemic injury.
- Добавил в систему: Хапчаев Шамиль Юсуфович