One-pot synthesis of 6'-amino-substituted spirooxazinesстатья
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Дата последнего поиска статьи во внешних источниках: 27 мая 2015 г.
Аннотация:A one-pot synthesis of 6'-amino-substituted spiroindolinonaphth[2, 1-b][1, 4]oxazines is developed through the condensation of 2-methylene-1,3,3-trimethylindoline derivatives and 1-amino-2-naphthol in the presence of different secondary amines and oxidizing agents using methanol or toluene as the solvent. The main advantage of the method is its simplicity, and starting from readily accessible reagents. it allows the preparation of amino derivatives of spironaphthoxazine with good yields under mild reaction conditions.