Structure, Function, and Therapeutic Potential of Marine Bioactive Peptidesстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 16 сентября 2020 г.
Аннотация:In recent years, bioactive peptides from marine organisms have gained increasing attention in the field of pharmaceutical, cosmeceutical, and nutraceutical product development owing to their interesting biological properties. They are involved in fundamental mechanisms that allow the survival of living organisms, including their defense, reproduction, growth, and homeostasis. Marine peptides that are diverse in structure and function have been found in various phyla, and their number has dynamically grown over the recent years. Some of them are evolutionary ancient molecular factors of innate immunity that play a key role in host defense. Long-term evolution of marine organisms proceeded in continuous contact with pathogens, and efficient defense mechanisms were the necessary condition of their survival. Peptides with protective functions were isolated from tissues of many marine invertebrates and vertebrates. A plethora of biological activities, including antibacterial, antifungal, antiviral, cytotoxic, neurotoxic, anticoagulant, antidiabetic, antifreeze, endotoxin-binding, and immune-modulating, make marine peptides an attractive molecular basis for the design of innovative antibiotics, anticancer drugs, analgetics, medicines for neurological disorders, etc.