Аннотация:An oxidative polymerization of flavonoid taxifolin (dihydroquercetin) in betaine-glycerin (B-G, 1: 2) as cosolventmedium has been performed using laccase from basidial fungus Trametes hirsuta as a biocatalyst and TEMPOas a redox mediator. The terminal oxidizing agent was atmospheric oxygen. Under optimal synthesis conditions,dihydroquercetin oligomers (oligo DHQ) with a weight average molecular weight of 1800 g / mol, a polydispersityindex of 1.09 and a yield of 57 ± 7% were obtained.