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Hysterical and Traumatic Peripheral Nerve Disorder: Immunology Aspectsстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 28 июля 2021 г.
- Авторы: Labunskiy D., Kiryukhina S., Podsevatkin V., Zheleznikova O., Kiryukhin F., Kolmykov V., Kurgaev N.
- Журнал: European Journal of Neurology
- Том: 27
- Номер: 1
- Год издания: 2020
- Издательство: Blackwell Publishing Inc.
- Местоположение издательства: United Kingdom
- Первая страница: 758
- Последняя страница: 758
- Номер статьи: EPO1370
- Аннотация: Background and aims: There are many causes of peripheral neuropathies. We observed and discussed here traumatic and, as an outcome, inflammatory neuropathy (TIN) on one hand, and peripheral nervous pathology caused by hysterical conversion personality disorder (CPDN), on another. Our goal was to study and compare main immunological involvement in both types of neuropathies including the study of IgG and inflammatory Methods: Control group included 54 healthy donors. All patient’s and donor’s groups included men and women aging by 17-62 year old. Ig G was detected using diffusion in gel by Mancini. Concentrations of all pro-inflammatory cytokines were measured by ELISA. We used meta-analysis for statistical evaluationof our results.Results: It was revealed that in 77% of TIN patients IgG and IL-6, IL-10, IL-11, IL-17 serum concentrations were markedly increased. In 48% of CPDN patients serum concentrations of these substances were also increased but in much lower extent. Conclusion: We know that the persons with hysterical personality have markedly higher level of interferon. Contrary to that, concentrations of pro-inflammatory cytokines were not significantly increased on these patients, but in case of traumatic and inflammatory neuropathies IgG and IL-6, IL-10, IL-11, IL-17, was substantially raised, which stressed their pathogenic role namely in these type of peripheral nerve lesions. Our finding will play an important role in future treatment modalities
- Добавил в систему: Кирюхина Светлана Владимировна
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | ene.14308_2.pdf | ene.14308_2.pdf | 32,0 МБ | 14 декабря 2020 [Kiryukhina] |