Transcriptional control of insulin-sensitive glucose carrier Glut4 expression in adipose tissue cellsстатья
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Дата последнего поиска статьи во внешних источниках: 18 ноября 2016 г.
Аннотация:In search for new targets for obesity treatment, we have studied the effect of several transcription factors on the conversion of murine preadipocytes from the 3T3-L1 cell line into adipocytes. We have found that knockdown of Prep1 gene expression affects adipogenic differentiation and results in significant increase in the insulin-sensitive glucose carrier Glut4 gene expression.