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Unsaturated and thiolated derivatives of polysaccharides as functional matrixes for tissue engineering and pharmacology: A reviewстатья
Статья опубликована в высокорейтинговом журнале
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 апреля 2021 г.
- Авторы: Farion Ivan A., Burdukovskii Vitalii F., Kholkhoev Bato Ch, Timashev Peter S.
- Журнал: Carbohydrate Polymers
- Том: 259
- Год издания: 2021
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- Номер статьи: 117735
- DOI: 10.1016/j.carbpol.2021.117735
- Аннотация: This review examines investigations into the functionalization of polysaccharides by substituents containing multiple (Cdouble bondC) bonds and thiol (SH) groups that are prone to (co)polymerization in the presence of thermal, redox and photoinitiators or Michael addition reactions. A comparative analysis of the approaches to grafting the mentioned substituents onto the polysaccharide macromolecules was conducted. The use of the modified polysaccharides for the design of the 3D structures, including for the development of the pore bearing matrixes of cells or scaffolds utilized in regenerative medicine was examined. These modified polymers were also examined toward the design of excipient matrixes in pharmacological compositions, including with controllable release of active pharmaceuticals, as wel as of antibacterial and antifungal agents and others. In addition, a few examples of the use of modified derivatives in other areas are given.
- Добавил в систему: Тимашев Петр Сергеевич