Design, Synthesis, and Some Aspects of the Biological Activity of Mitochondria-Targeted Antioxidantsстатья
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Дата последнего поиска статьи во внешних источниках: 23 ноября 2017 г.
Аннотация:This review summarizes for the first time data on the design and synthesis of biologically active compounds of a new generation - mitochondria-targeted antioxidants, which are natural (or synthetic) p-benzoquinones conjugated via a lipophilic linker with (triphenyl) phosphonium or ammonium cations with delocalized charge. It also describes the synthesis of mitochondria-targeted antioxidants - uncouplers of oxidative phosphorylation - based on fluorescent dyes.