Synthesis and Chemical Transformations of 7-Hydroxybicyclo[3.3.1]nonane-3-carbohydrazideстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 4 июня 2021 г.
Аннотация:The reaction of 4-oxahomoadamantan-5-one with hydrazine gave (3-exo,7-endo)-7-hydroxybicyclo[3.3.1]nonane-3-carbohydrazide. The latter was reacted with benzonitrile, formamide, and p-(trifluoromethyl)benzaldehyde to obtain a number of new bicyclo[3.3.1]nonane derivatives. The structural features of the new compounds were studied using 2D NMR spectroscopy and XRD analysis. The synthesized bicyclo[3.3.1]nonanes can be used in the directed synthesis of compounds of high molecular complexity for biological activity testing.