Factors Influencing Immunity Toward SARS-CoV-2 Infection

Wajdy, A.; bawareed, O.A.; Nime, R.; Sorokina, A.; Lukyanova, E.; Abakirov, M.; Nurmukhametov, R.; Gushchina, Y.; Alsmadi, Y.; Troshin, V.; Kozlov, Y.; Elena, P.; Anton, P.; Jarrar, Y.; Al-Ameer, H.J.; Al-Turk, H.; Hadi1, N.R.

Авторы: Wajdy Al-Awaida, bawareed Omar Al, Nime Refat, Sorokina Anna, Lukyanova Elena, Abakirov Medetbek, Nurmukhametov Rinat, Gushchina Yulia, Alsmadi Yaseen, Troshin Vladimir, Kozlov Yaroslav, Elena Pavlikova, Anton Potapenko, Jarrar Yazun, Al-Ameer Hamzeh J., Al-Turk Hadeel, Hadi1 Najah R.
Журнал: SSRN Electronic Journal
Том: 11
Номер: 8
Год издания: 2021
Издательство: Elsevier B.V.
Местоположение издательства: Netherlands
Первая страница: 263
Последняя страница: 264
Аннотация: The coronavirus disease (COVID-19) is a highly pathogenic viral infection caused bySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2). World Health Organization(WHO) announced the COVID-19 outbreak as a pandemic on 11 March 2020. The B cells in our immune system play a major role in protecting against viruses, bacterium, or other pathogens by producing different classes of antibodies. This study aimed to evaluate the correlation between antibodies production (IgG and IgM) and several factors; age, sex, comorbidity diseases, patient’s blood group, and Chest computed tomography (CT) findings. IgG and IgM antibody levels were determined for 500 COVID-19 Russian patients. There was a significant inverse correlation (χ2 = 92.53, df = 2, P < 0.001) between IgG antibody production and disease severity determined by CT scan. However, other clinical factors, such as blood group, and co-morbidity diseases, were not significantly associated with antibody production among COVID-19 patients. from the results in this study show that lung damage finding in CT decreases the immune system’s capacity and worsens symptoms and severity of COVID-19
Добавил в систему: Клементьева Анна Григорьевна

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Factors Influencing Immunity Toward SARS-CoV-2 Infectionстатья

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