Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteers

Makmatov-Rys, M.; Glazkov, A.; Raznitsyna, I.; Kulikov, D.; Molochkov, A.; Khlebnikova, A.; Kaznacheeva, E.; Sekirin, A.; Rogatkin, D.

Авторы: Makmatov-Rys Mikhail, Glazkov Alexey, Raznitsyna Irina, Kulikov Dmitriy, Molochkov Anton, Khlebnikova Albina, Kaznacheeva Ekaterina, Sekirin Alexey, Rogatkin Dmitry
Сборник: Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020)
Год издания: 2020
Место издания: SCITEPRESS - Science and Technology Publications
Первая страница: 73
Последняя страница: 78
DOI: 10.5220/0009177000730078
Аннотация: Currently, in clinical practice, the assessment of ultraviolet (UV) -induced erythema and the determinationof the minimal erythema dose (MED) is done visually, which is subjective, inaccurate and associated withhigh variability of the results. To solve this problem, the application of optical methods seems promising,allowing us to evaluate changes in epidermis and dermis induced by UV exposure. In this study the analysisof endogenous fluorescence and microcirculation characteristics by non-invasive optical methods revealedthe relationship between the intensity of endogenous fluorescence of porphyrins and oxygen consumptionwith a dose of UV radiation. The correlation of the intensity of endogenous fluorescence of the irradiatedregion normalized to intact tissue with a dose of UV was demonstrated. Therefore, optical diagnostic methodscan be a promising tool for non-invasive and quantitative assessment of UV erythema and MED.
Добавил в систему: Разницына Ирина Андреевна

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Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteersстатья