Experimental Simulation of Volume Repainting Technique at Proton Synchrotron in Context of Spot Scanning Proton Therapy

Belikhin, M.A.; Chernyaev, A.P.; Pryanichnikov, A.A.; Shemyakov, A.E.

Авторы: Belikhin M.A., Chernyaev A.P., Pryanichnikov A.A., Shemyakov A.E.
Сборник: Proc. RuPAC'21
Серия: Russian Particle Accelerator Conference
Год издания: 2021
Издательство: Joint Accelerator Conferences Website Publishing
Местоположение издательства: Geneva, Switzerland
Первая страница: 192
Последняя страница: 195
DOI: 10.18429/JACOW-RUPAC2021-MOPSA45
Аннотация: Background: Reduction the influence of respiration-induced intrafractional motion of tissues is one of the main tasks of proton therapy with a scanning beam. Repainting is one of the techniques of motion compensation. It consists in multiple repeated irradiations of the entire volume or individual iso-energy layers with a dose that is a multiple of the prescribed dose. As a result, the dose is averaged, which leads to an increase in the uniformity of the dose field. Purpose: Experimental simulation of volume sequential repainting and dosimetric estimation of its capabilities in the context of spot scanning proton therapy (SSPT) using dynamic phantom. Materials and Methods: Simulation of respiration-like translational motion is performed using the non-anthropomorphic water dynamic phantom. Target of this phantom is compatible with EBT-3 films. Estimation of repainting technique is based on the analysis of average dose, dose uniformity in region of interests located within planning target volume, and dose gradients. Results: Repainting was estimated for motion with amplitudes of 2, 5, 10 mm with different number of iterations up to 10 at the prescribed dose of 6 Gy. This one increased the uniformity of the dose field from 85,9% to 96,0% at an amplitude of 10 mm and 10 iterations. Conclusions: Volume repainting improves the uniformity of dose distribution. However, the irradiation time increases, and the dose gradients deteriorate in proportion to the amplitude of motion.
Добавил в систему: Пряничников Александр Александрович

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Experimental Simulation of Volume Repainting Technique at Proton Synchrotron in Context of Spot Scanning Proton Therapyстатья

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