Аннотация:Primary headaches are highly prevalent and represent a major cause of disabilityin young adults. Neurofeedback is increasingly used in the treatment of chronicpain; however, there are few studies investigating its efficacy in patients withheadaches. We report the results of a cross-over sham-controlled study on theefficacy of neurofeedback in the prophylactic treatment of tension-type headache(TTH). Participants received ten sessions of infra-low frequency electroencephalographicneurofeedback and ten sessions of sham-neurofeedback, with the order of treatmentsbeing randomized. The study also included a basic psychotherapeutic intervention —a psychoeducational session performed before the main study phases and emotionalsupport provided throughout the study period. The headache probability was modeledas a function of the neurofeedback and sham-neurofeedback sessions performed todate. As a result, we revealed a strong beneficial effect of neurofeedback and noinfluence of the sham sessions. The study supports the prophylactic use of infra-lowfrequency neurofeedback in patients with TTH. From a methodological point of view, weadvocate for the explicit inclusion of psychotherapeutic components in neurofeedbackstudy protocols.