Scanning probe microscopy of biomacromolecules: nucleic acids, proteins and their complexes

Авторы: Kiselyova O.I., Gallyamov M.O., Nasikan N.S., Yaminsky I.V., Karpova O.V., Novikov V.K.
Сборник: Frontiers of Multifunctional Nanosystems
Серия: NATO Science Series II: Mathematics, Physics and Chemistry
Том: 57
Год издания: 2002
Место издания: Kluwer Academic Publishers Dordrecht
Первая страница: 321
Последняя страница: 330
DOI: 10.1007/978-94-010-0341-4_24
Аннотация: After successful imaging of DNA biomacromolecules using scanning probe microscopy (SPM) (Bustamante et al., 1992) much progress was achieved in the visualization of their different morphological features in air and liquid environments: cruciforms, R-loops, etc. SPM gives an opportunity for real-time studies of conformational changes of DNA molecules induced by chemical reagents - formation of torroidal and rod-like structures. Recently, SPM has greatly assisted in the measurements of electrical conductivity of individual DNA molecules (Kasumov et al., 2001). SPM opens new possibilities in the study of single macromolecule micromechanics: rigidity, strength of chemical bond and adhesion.
Добавил в систему: Галлямов Марат Олегович

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